"This is the only treatment for Melasma that I know it works and I trust." Nastaran, Owner


A Cosmelan® peel reduces and eliminates acquired skin blemishes of melanic origin, increasing skin luminosity and equalising skin tone

Cosmelan® is the leading depigmentation treatment in the world that treats all types of pigmentation.  

Cosmelan® peel differs from other skin brightening chemical peels in its ingredients, it goes after abnormality. It is designed to treat the specific symptoms of Melasma. Cosmelan® treatments can improve the appearance of:


·        Lentigo, Freckles or Nevus

·        Pregnancy Mask / Melasma

·        Pigmentation

·        Chloasma from UV damage

·        Birthmarks

·        Post-inflammatory hyperpigmentation (from acne / scars)

What types of pigmentation can be treated:

All types of pigmentation and skin colour can be effectively treated with the Cosmelan Depigmentation Peel, including hormonal pigmentation such as Melasma.

How does it work?

Action Mechanism:

Cosmelan® aims to reduce and eliminate skin blemishes of melanic origin.

Application of Cosmelan inhibits the melanogenesis process paralysing melanin production for a long period of time during which corneum stratum flaking plus the action of the macrophagic cells taking the melanin deposits with them.

Inhibitor action without damaging melanocyte

Under no circumstance does tyrosinase inhibition make the melanocytes disappear, but simply paralyses or stops melanin production, without risk of white blemishes appearing. Cosmelan action causes complementary inhibition of other enzymes involved in the eumelanin production process, like dopa tautomerase, among others.

Reversible inhibition of tyrosinase activity

Inhibition of the tyrosinase is only activated during treatment application. When finished, the enzyme recovers its activity producing new melanin, particularly if there is solar stimulus. Due to this, application of topical depigmentants must be reiterative to obtain results.


Properties: Cosmelan 1 mask and Cosmelan 2 maintenance treatment formulas act on the different melanogenesis stages to increase effects and achieve certain synergy. they have been developed from vegetable and chemical origin to guarantee maximum level of tyrosinase inhibition.

·         Rapid lightening action:

Intervening in the advanced stage of melanogenesis.

·         For all kinds of skin blemishes of melanic origin:

Particularly efficient in reducing localised epidermis blemishes.

·         Any season of the year:

even in summer, followed by use of total sunscreen to guarantee treatment effectiveness (Melan 130, Mesotech, complete moisturising sunblock or dermatological complete sunblock by Mesoestetic)

·         Good tolerance, all skin photo types:

All Cosmelan formulas have been rigorously prepared to guarantee maximum tolerance. Apt for all photo types and cases.

·         Proven efficiency:

Numerous “in vivo” and “in vitro” tests performed.

·         Lightening and luminosity:

It contains embellishing agents which equalise skin tone giving it luminosity.